Journal article
Sex steroids levels in chronic kidney disease and kidney transplant recipients: Associations with disease severity and prediction of mortality
M Grossmann, R Hoermann, M Ng Tang Fui, JD Zajac, FL Ierino, MA Roberts
Clinical Endocrinology | WILEY | Published : 2015
DOI: 10.1111/cen.12656
Abstract
Objective Our objective was to characterize and evaluate prognostic implications of circulating sex steroids in patients at different stages of chronic kidney disease (CKD). Design Prospective observational cohort study. Patients We prospectively recruited patients with CKD III-IV, undergoing chronic dialysis and kidney transplant recipients (KTR) from a single centre in 2003-2004. Measurements Two stored samples taken 3 months apart were analysed for sex hormones using liquid chromatography/tandem mass spectrometry, and the mean of the two was used for analysis. We also measured novel biomarkers troponin T and NT-proBNP. Patients were followed until death, transplant or 30 June 2013, and su..
View full abstractGrants
Awarded by National Health and Medical Research Council of Australia Career Development Fellowship
Funding Acknowledgements
M Grossmann was supported by a National Health and Medical Research Council of Australia Career Development Fellowship (# 1024139). The authors thank Professor David Power, Department of Nephrology, Austin Health, for contributing Research funds to perform the sex hormone assays in this study.